The Effect of KatG S315t M. Tuberculosis Gene Mutation on Conversion Rate of MDR-TB Patients with Shorter-Course Treatment

Background. Resistance to the INH drug is most often caused by a mutation of the KatG S315T M.Tb gene. MDR TB treatment with short-term WHO mixes using high-dose INH drugs is considered less effective in this mutation condition because it causes high resistance to INH. The effectiveness of MDR TB tr...

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Bibliographic Details
Main Authors: Raden Ayu Linda Andriani, Zen Ahmad
Format: Article
Language:English
Published: Universitas Sriwijaya 2020-10-01
Series:Bioscientia Medicina: Journal of Biomedicine and Translational Research
Subjects:
Online Access:https://bioscmed.com/index.php/bsm/article/view/158