Behavioral abnormalities and Parkinson’s-like histological changes resulting from Id2 inactivation in mice

SUMMARY Characterizing dopaminergic neuronal development and function in novel genetic animal models might uncover strategies for researchers to develop disease-modifying treatments for neurologic disorders. Id2 is a transcription factor expressed in the developing central nervous system. Id2−/− mic...

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Bibliographic Details
Main Authors: Matthew C. Havrda, Brenton R. Paolella, Nora M. Ward, Kathryn B. Holroyd
Format: Article
Language:English
Published: The Company of Biologists 2013-05-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/6/3/819