Modulation of CD8+ memory stem T cell activity and glycogen synthase kinase 3β inhibition enhances anti-tumoral immunity in gastric cancer

Modulation of CD8+ memory stem T cell activity and glycogen synthase kinase 3β inhibition enhances anti-tumoral immunity in gastric cancer

The potential contributions of CD8+ memory stem T cells to anti-tumor immunity and immunotherapy responses in gastric cancer has not been demonstrated. We found that CD8+ memory stem T cell frequencies were increased in the peripheral blood of gastric cancer patients compared to healthy donors and d...

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Bibliographic Details
Main Authors: Jin-yu Zhang, Yong-liang Zhao, Yi-pin Lv, Ping Cheng, Weisan Chen, Mubin Duan, Yong-sheng Teng, Ting-ting Wang, Liu-sheng Peng, Fang-yuan Mao, Yu-gang Liu, Xiao-long Fu, Pei-wu Yu, Ping Luo, Wei-jun Zhang, Quan-ming Zou, Yuan Zhuang
Format: Article
Language:English
Published: Taylor & Francis Group 2018-04-01
Series:OncoImmunology
Subjects:
cd8+ t cells
fasl
gastric cancer
gsk-3β
tscm cells
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1412900

Internet

http://dx.doi.org/10.1080/2162402X.2017.1412900

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