Complex Minigene Library Vaccination for Discovery of Pre-Erythrocytic Plasmodium T Cell Antigens.

Development of a subunit vaccine targeting liver-stage Plasmodium parasites requires the identification of antigens capable of inducing protective T cell responses. However, traditional methods of antigen identification are incapable of evaluating T cell responses against large numbers of proteins e...

Full description

Bibliographic Details
Main Authors: Brad C Stone, Arnold Kas, Zachary P Billman, Deborah H Fuller, James T Fuller, Jay Shendure, Sean C Murphy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4829254?pdf=render