CD8+ T cells as a source of IFN-γ production in human cutaneous leishmaniasis.

CD8+ T cells as a source of IFN-γ production in human cutaneous leishmaniasis.

BACKGROUND: In human leishmaniasis Th1/Th2 dichotomy similar to murine model is not clearly defined and surrogate marker(s) of protection is not yet known. In this study, Th1/Th2 cytokines (IL-5, IL-10, IL-13 and IFN-γ) profile induced by purified CD4(+)/CD8(+) T cells in response to Leishmania anti...

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Bibliographic Details
Main Authors: Mahmoud Nateghi Rostami, Hossein Keshavarz, Rosita Edalat, Abdolfattah Sarrafnejad, Tahereh Shahrestani, Fereidoun Mahboudi, Ali Khamesipour
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC2953482?pdf=render

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http://europepmc.org/articles/PMC2953482?pdf=render

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