Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans

Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans

Abstract Background Dusp8 is the first GWAS‐identified gene that is predominantly expressed in the brain and has previously been linked with the development of diabetes type 2 in humans. In this study, we unravel how Dusp8 is involved in the regulation of sucrose reward behavior. Methods Female, cho...

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Bibliographic Details
Main Authors: Peter Baumann, Sonja C. Schriever, Stephanie Kullmann, Annemarie Zimprich, Andreas Peter, Valerie Gailus‐Durner, Helmut Fuchs, Martin Hrabe de Angelis, Wolfgang Wurst, Matthias H. Tschöp, Martin Heni, Sabine M. Hölter, Paul T. Pfluger
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Brain and Behavior
Subjects:
dopamine
Dusp8
MAP kinase
sucrose reward
Online Access:https://doi.org/10.1002/brb3.1928

Internet

https://doi.org/10.1002/brb3.1928

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