Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape

Anti-tumor immunity induced by ectopic expression of viral antigens is transient and limited by immune escape

Immunotherapeutic treatments in head and neck cancer clinical trials include cancer vaccines targeting foreign viral antigens or mutational neoantigens derived from cancer-expressed proteins. Anti-tumor immune responses place cancer cells under selective pressure to lose or downregulate target antig...

Full description

Bibliographic Details
Main Authors: Neeraja Dharmaraj, Stacey L. Piotrowski, Chen Huang, Jared M. Newton, Leonard S. Golfman, Aurelie Hanoteau, Sandeep T. Koshy, Aileen W. Li, Merlyn X. Pulikkathara, Bing Zhang, Jared K. Burks, David J. Mooney, Yu L. Lei, Andrew G. Sikora, Simon Young
Format: Article
Language:English
Published: Taylor & Francis Group 2019-04-01
Series:OncoImmunology
Subjects:
immune editing
immunotherapy
biomaterials
mesoporous silica rods
cancer vaccine
head and neck cancer
hpv16 e6 and e7
Online Access:http://dx.doi.org/10.1080/2162402X.2019.1568809

Internet

http://dx.doi.org/10.1080/2162402X.2019.1568809

Similar Items