Cohesin and polycomb proteins functionally interact to control transcription at silenced and active genes.

Cohesin is crucial for proper chromosome segregation but also regulates gene transcription and organism development by poorly understood mechanisms. Using genome-wide assays in Drosophila developing wings and cultured cells, we find that cohesin functionally interacts with Polycomb group (PcG) silen...

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Bibliographic Details
Main Authors: Cheri A Schaaf, Ziva Misulovin, Maria Gause, Amanda Koenig, David W Gohara, Audrey Watson, Dale Dorsett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3688520?pdf=render