Reversible and rapid transfer-RNA deactivation as a mechanism of translational repression in stress.

Stress-induced changes of gene expression are crucial for survival of eukaryotic cells. Regulation at the level of translation provides the necessary plasticity for immediate changes of cellular activities and protein levels. In this study, we demonstrate that exposure to oxidative stress results in...

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Bibliographic Details
Main Authors: Andreas Czech, Sandra Wende, Mario Mörl, Tao Pan, Zoya Ignatova
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-08-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3757041?pdf=render