Characterization and Evaluation of Two Novel Fluorescent Sigma-2 Receptor Ligands as Proliferation Probes

We synthesized and characterized two novel fluorescent sigma-2 receptor selective ligands, SW120 and SW116, and evaluated these ligands as potential probes for imaging cell proliferation. Both ligands are highly selective for sigma-2 receptors versus sigma-1 receptors. SW120 and SW116 were internali...

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Bibliographic Details
Main Authors: Chenbo Zeng, Suwanna Vangveravong, Lynne A. Jones, Krzysztof Hyrc, Katherine C. Chang, Jinbin Xu, Justin M. Rothfuss, Mark P. Goldberg, Richard S. Hotchkiss, Robert H. Mach
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2011-11-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2011.00009