Immobilized artificial membrane chromatography: from medicinal chemistry to environmental sciences

Immobilized artificial membrane chromatography: from medicinal chemistry to environmental sciences

Immobilized Artificial Membrane (IAM) chromatography constitutes a valuable tool for medicinal chemists to prioritize drug candidates in early drug development. The retention on IAM stationary phases encodes lipophilicity, electrostatic and other secondary interactions contrary to traditional octano...

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Bibliographic Details
Main Authors: Fotis Tsopelas, Chrysanthos Stergiopoulos, Anna Tsantili-Kakoulidou
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2018-09-01
Series:ADMET and DMPK
Subjects:
: IAM chromatography
lipophilicity
phospholipophilicity, membrane permeability
human oral absorption
ecotoxicity
aquatic toxicity
bioconcentration factor (BCF)
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/553

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http://pub.iapchem.org/ojs/index.php/admet/article/view/553

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