Genome-Wide Differentially Methylated Region Analysis to Reveal Epigenetic Differences of Articular Cartilage in Kashin–Beck Disease and Osteoarthritis

Genome-Wide Differentially Methylated Region Analysis to Reveal Epigenetic Differences of Articular Cartilage in Kashin–Beck Disease and Osteoarthritis

Kashin–Beck disease (KBD) is a degenerative osteoarticular disorder, and displays the significant differences with osteoarthritis (OA) regarding the etiology and molecular changes in articular cartilage. However, the underlying dysfunctions of molecular mechanisms in KBD and OA remain unclear. Here,...

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Bibliographic Details
Main Authors: Yue Fan, Dalong Gao, Yingang Zhang, Jiaqiang Zhu, Feng Zhang, Lu Wang, Yan Wen, Xiong Guo, Shiquan Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
differentially methylated region
Kashin–Beck disease
osteoarthritis
articular cartilage
DNA methylation
cartilage
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.636291/full

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https://www.frontiersin.org/articles/10.3389/fcell.2021.636291/full

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