Ex-vivo assessment of drug response on breast cancer primary tissue with preserved microenvironments

Ex-vivo assessment of drug response on breast cancer primary tissue with preserved microenvironments

Interaction between cancerous, non-transformed cells, and non-cellular components within the tumor microenvironment plays a key role in response to treatment. However, short-term culture or xenotransplantation of cancer specimens in immunodeficient animals results in dramatic modifications of the tu...

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Bibliographic Details
Main Authors: Manuele G. Muraro, Simone Muenst, Valentina Mele, Luca Quagliata, Giandomenica Iezzi, Alexandar Tzankov, Walter P. Weber, Giulio C. Spagnoli, Savas D. Soysal
Format: Article
Language:English
Published: Taylor & Francis Group 2017-07-01
Series:OncoImmunology
Subjects:
breast cancer
ctla-4
immune checkpoint inhibitors
pd-l1
tissue engineering
tumor microenvironment
Online Access:http://dx.doi.org/10.1080/2162402X.2017.1331798

Internet

http://dx.doi.org/10.1080/2162402X.2017.1331798

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