Biosynthetic and Synthetic Strategies for Assembling Capuramycin-Type Antituberculosis Antibiotics

Biosynthetic and Synthetic Strategies for Assembling Capuramycin-Type Antituberculosis Antibiotics

<i>Mycobacterium tuberculosis </i><i>(Mtb)</i> has recently surpassed HIV/AIDS as the leading cause of death by a single infectious agent. The standard therapeutic regimen against tuberculosis (TB) remains a long, expensive process involving a multidrug regimen, and the promi...

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Bibliographic Details
Main Authors: Ashley L. Biecker, Xiaodong Liu, Jon S. Thorson, Zhaoyong Yang, Steven G. Van Lanen
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Molecules
Subjects:
natural product
nucleoside
antibiotic
MraY
bacterial translocase I
<i>Mycobacterium tuberculosis</i>
Online Access:https://www.mdpi.com/1420-3049/24/3/433

Internet

https://www.mdpi.com/1420-3049/24/3/433

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