To Be or Not To Be T4: Evidence of a Complex Evolutionary Pathway of Head Structure and Assembly in Giant Salmonella Virus SPN3US

To Be or Not To Be T4: Evidence of a Complex Evolutionary Pathway of Head Structure and Assembly in Giant Salmonella Virus SPN3US

Giant Salmonella phage SPN3US has a 240-kb dsDNA genome and a large complex virion composed of many proteins for which the functions of most are undefined. We recently determined that SPN3US shares a core set of genes with related giant phages and sequenced and characterized 18 amber mutants to faci...

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Bibliographic Details
Main Authors: Bazla Ali, Maxim I. Desmond, Sara A. Mallory, Andrea D. Benítez, Larry J. Buckley, Susan T. Weintraub, Michael V. Osier, Lindsay W. Black, Julie A. Thomas
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Microbiology
Subjects:
Salmonella
myovirus
giant phage
mass spectrometry
prohead protease
CTS (capsid targeting sequence)
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02251/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.02251/full

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