Proteoglycan serglycin promotes non-small cell lung cancer cell migration through the interaction of its glycosaminoglycans with CD44

Proteoglycan serglycin promotes non-small cell lung cancer cell migration through the interaction of its glycosaminoglycans with CD44

Abstract Background Serglycin (SRGN), previously recognized as an intracellular proteoglycan involved in the storage processes of secretory granules, has recently been shown to be upregulated in several solid tumors. We have previously shown that SRGN in non-small cell lung cancer (NSCLC) promotes m...

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Bibliographic Details
Main Authors: Jing-You Guo, Chu-Hsuan Chiu, Mei-Jung Wang, Fu-An Li, Jeou-Yuan Chen
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Journal of Biomedical Science
Subjects:
CD44
Cell migration
Chondroitin sulfate glycosaminoglycan
Proteoglycan
Serglycin
Glycoaminoglycans
Online Access:https://doi.org/10.1186/s12929-019-0600-3

Internet

https://doi.org/10.1186/s12929-019-0600-3

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