Aging and Microglial Response following Systemic Stimulation with <i>Escherichia coli</i> in Mice

Aging and Microglial Response following Systemic Stimulation with <i>Escherichia coli</i> in Mice

Systemic infection is an important risk factor for the development cognitive impairment and neurodegeneration in older people. Animal experiments show that systemic challenges with live bacteria cause a neuro-inflammatory response, but the effect of age on this response in these models is unknown. Y...

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Bibliographic Details
Main Authors: Inge C.M. Hoogland, Dunja Westhoff, Joo-Yeon Engelen-Lee, Mercedes Valls Seron, Judith H.M.P. Houben-Weerts, David J. van Westerloo, Tom van der Poll, Willem A. van Gool, Diederik van de Beek
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cells
Subjects:
microglia
microglial activation
systemic infection
<i>Escherichia coli</i>
neuro-inflammation
ageing
Online Access:https://www.mdpi.com/2073-4409/10/2/279

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https://www.mdpi.com/2073-4409/10/2/279

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