Long Non-coding RNA SOX2OT: Expression Signature, Splicing Patterns and Emerging Roles in Pluripotency and Tumorigenesis

Long Non-coding RNA SOX2OT: Expression Signature, Splicing Patterns and Emerging Roles in Pluripotency and Tumorigenesis

SOX2 overlapping transcript (SOX2OT) is a long non-coding RNA (lncRNA) which harbors one of the major regulators of pluripotency, SOX2 gene, in its intronic region. SOX2OT gene is mapped to human chromosome 3q26.3 (Chr3q26.3) locus and is extended in a high conserved region of over 700 kb. Little is...

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Bibliographic Details
Main Authors: Alireza eShahryari, Marie eSaghaeian Jazi, Nader eMansour Samaei, Seyed Javad eMowla
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Genetics
Subjects:
splicing pattern
stem cell
lncRNA
expression signature
sox2ot
pluripotency; tumorigenesis
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00196/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00196/full

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