Modulation of steroidogenesis by Actaea racemosa and vitamin C combination, in letrozole induced polycystic ovarian syndrome rat model: promising activity without the risk of hepatic adverse effect

Modulation of steroidogenesis by Actaea racemosa and vitamin C combination, in letrozole induced polycystic ovarian syndrome rat model: promising activity without the risk of hepatic adverse effect

Abstract Background Complementary remedies such as the Chinese herb ‘Sheng Ma’ (Black cohosh; Actaea racemosa ‘AR’) are being sought to overcome the shortcomings of conventional hormonal and surgical therapies developed for the treatment of polycystic ovary syndrome (PCOS). However, AR-induced hepat...

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Bibliographic Details
Main Authors: Asmaa A. Azouz, Sara E. Ali, Reham M. Abd-Elsalam, Shimaa R. Emam, Mona K. Galal, Sherif H. Elmosalamy, Muhammed A. Alsherbiny, Bardes B. Hassan, Chun Guang Li, Shymaa A. El Badawy
Format: Article
Language:English
Published: BMC 2021-04-01
Series:Chinese Medicine
Subjects:
Actaea racemosa
Vitamin C
Polycystic ovarian syndrome
Hepatotoxicity
PCOS rat model
UPLC-QTOF-MS
Online Access:https://doi.org/10.1186/s13020-021-00444-z

Internet

https://doi.org/10.1186/s13020-021-00444-z

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