Dynamic action of the Sec machinery during initiation, protein translocation and termination

Protein translocation across cell membranes is a ubiquitous process required for protein secretion and membrane protein insertion. In bacteria, this is mostly mediated by the conserved SecYEG complex, driven through rounds of ATP hydrolysis by the cytoplasmic SecA, and the trans-membrane proton moti...

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Bibliographic Details
Main Authors: Tomas Fessl, Daniel Watkins, Peter Oatley, William John Allen, Robin Adam Corey, Jim Horne, Steve A Baldwin, Sheena E Radford, Ian Collinson, Roman Tuma
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/35112