GPS-PBS: A Deep Learning Framework to Predict Phosphorylation Sites that Specifically Interact with Phosphoprotein-Binding Domains

GPS-PBS: A Deep Learning Framework to Predict Phosphorylation Sites that Specifically Interact with Phosphoprotein-Binding Domains

Protein phosphorylation is essential for regulating cellular activities by modifying substrates at specific residues, which frequently interact with proteins containing phosphoprotein-binding domains (PPBDs) to propagate the phosphorylation signaling into downstream pathways. Although massive phosph...

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Bibliographic Details
Main Authors: Yaping Guo, Wanshan Ning, Peiran Jiang, Shaofeng Lin, Chenwei Wang, Xiaodan Tan, Lan Yao, Di Peng, Yu Xue
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
protein phosphorylation
phosphoprotein-binding domain
phosphorylation site
PPBD-specific binding p-site
deep learning
protein kinase
Online Access:https://www.mdpi.com/2073-4409/9/5/1266

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https://www.mdpi.com/2073-4409/9/5/1266

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