Comparative Study of Transcriptomics-Based Scoring Metrics for the Epithelial-Hybrid-Mesenchymal Spectrum

Comparative Study of Transcriptomics-Based Scoring Metrics for the Epithelial-Hybrid-Mesenchymal Spectrum

The Epithelial–mesenchymal transition (EMT) is a cellular process implicated in embryonic development, wound healing, and pathological conditions such as cancer metastasis and fibrosis. Cancer cells undergoing EMT exhibit enhanced aggressive behavior characterized by drug resistance, tumor-initiatio...

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Bibliographic Details
Main Authors: Priyanka Chakraborty, Jason T. George, Shubham Tripathi, Herbert Levine, Mohit Kumar Jolly
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
EMT
MET
EMT score
EMT quantification
tumor heterogeneity
hybrid epithelial/mesenchymal
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00220/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00220/full

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