Studies on the binding affinity of anticancer drug mitoxantrone to chromatin, DNA and histone proteins
<p>Abstract</p> <p>Mitoxantrone is a potent antitumor drug, widely used in the treatment of various cancers. In the present study, we have investigated and compared the affinity of anticancer drug, mitoxantrone, to EDTA-soluble chromatin (SE-chromatin), DNA and histones employing U...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-03-01
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| Series: | Journal of Biomedical Science |
| Online Access: | http://www.jbiomedsci.com/content/16/1/31 |