Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay

Identification of RSK and TTK as Modulators of Blood Vessel Morphogenesis Using an Embryonic Stem Cell-Based Vascular Differentiation Assay

Blood vessels are formed through vasculogenesis, followed by remodeling of the endothelial network through angiogenesis. Many events that occur during embryonic vascular development are recapitulated during adult neoangiogenesis, which is critical to tumor growth and metastasis. Current antiangiogen...

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Bibliographic Details
Main Authors: Lamis Hammoud, Jessica R. Adams, Amanda J. Loch, Richard C. Marcellus, David E. Uehling, Ahmed Aman, Christopher Fladd, Trevor D. McKee, Christine E.B. Jo, Rima Al-Awar, Sean E. Egan, Janet Rossant
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116301710

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http://www.sciencedirect.com/science/article/pii/S2213671116301710

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