Molecular evidence of sequential evolution of DDT- and pyrethroid-resistant sodium channel in Aedes aegypti.

<h4>Background</h4>Multiple mutations in the voltage-gated sodium channel have been associated with knockdown resistance (kdr) to DDT and pyrethroid insecticides in a major human disease vector Aedes aegypti. One mutation, V1016G, confers sodium channel resistance to pyrethroids, but a d...

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Bibliographic Details
Main Authors: Mengli Chen, Yuzhe Du, Shaoying Wu, Yoshiko Nomura, Guonian Zhu, Boris S Zhorov, Ke Dong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007432