ΔNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation

<p>Abstract</p> <p>Background</p> <p>ΔNp63α is an epithelial progenitor cell marker that maintains epidermal stem cell self-renewal capacity. Previous studies revealed that UV-damage induced p53 phosphorylation is confined to ΔNp63α-positive cells in the basal layer of...

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Bibliographic Details
Main Authors: Smith Graeme, DiRenzo James, Gueven Nuri, Hrstka Roman, Nekulova Marta, Finlan Lee E, Holcakova Jitka, Craig Ashley L, Hupp Ted R, Vojtesek Borivoj
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/195