Recovirus NS1-2 Has Viroporin Activity That Induces Aberrant Cellular Calcium Signaling To Facilitate Virus Replication

Tulane virus is one of many enteric caliciviruses that cause acute gastroenteritis and diarrheal disease. Globally, enteric caliciviruses affect both humans and animals and amass >65 billion dollars per year in treatment and health care-associated costs, thus imposing an enormous economic burden....

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Bibliographic Details
Main Authors: Alicia C. Strtak, Jacob L. Perry, Mark N. Sharp, Alexandra L. Chang-Graham, Tibor Farkas, Joseph M. Hyser
Format: Article
Language:English
Published: American Society for Microbiology 2019-09-01
Series:mSphere
Subjects:
Online Access:https://doi.org/10.1128/mSphere.00506-19