Chromosome 2q gain and epigenetic silencing of GATA3 in microglandular adenosis of the breast

Chromosome 2q gain and epigenetic silencing of GATA3 in microglandular adenosis of the breast

Abstract Microglandular adenosis (MGA) represents a rare neoplasm of the mammary gland, which in a subset of cases may be associated with triple‐negative breast cancer (BC). The biology of MGA is poorly understood. In this study, eight MGA cases (n = 4 with and n = 4 without associated BC) were subj...

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Bibliographic Details
Main Authors: Martin Radner, Jana Lisa vanLuttikhuizen, Stephan Bartels, Janin Bublitz, Isabel Grote, Luisa Rieger, Henriette Christgen, Helge Stark, Christopher Werlein, Marcel Lafos, Doris Steinemann, Ulrich Lehmann, Matthias Christgen, Hans Kreipe
Format: Article
Language:English
Published: Wiley 2021-05-01
Series:The Journal of Pathology: Clinical Research
Subjects:
breast cancer precursor
triple‐negative breast cancer
luminal differentiation
stem cell
DNA methylation
epigenetic alteration
Online Access:https://doi.org/10.1002/cjp2.195

Internet

https://doi.org/10.1002/cjp2.195

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