Synthesis of New 5-Aryl-benzo[f][1,7]naphthyridines via a Cascade Process (Ugi-3CR/Intramolecular Aza-Diels-Alder Cycloaddition)/Aromatization

Synthesis of New 5-Aryl-benzo[f][1,7]naphthyridines via a Cascade Process (Ugi-3CR/Intramolecular Aza-Diels-Alder Cycloaddition)/Aromatization

A series of eight new 5-aryl-benzo[f][1,7]naphthyridines were synthesized in 17 to 64% overall yields via an improved MW-assisted cascade-like one pot process (Ugi–three component reaction/intramolecular aza-Diels-Alder cycloaddition) coupled to an aromatization process from tri-functional...

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Bibliographic Details
Main Authors: Óscar Vázquez-Vera, Daniel Segura-Olvera, Mónica A. Rincón-Guevara, Atilano Gutiérrez-Carrillo, Miguel A. García-Sánchez, Ilich A. Ibarra, Leticia Lomas-Romero, Alejandro Islas-Jácome, Eduardo González-Zamora
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
one-pot procedures
cascade processes
multicomponent reactions
aza-Diels-Alder cycloadditions
aromatization
microwave assisted synthesis
benzo[f][1,7]naphthyridines
Online Access:http://www.mdpi.com/1420-3049/23/8/2029

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http://www.mdpi.com/1420-3049/23/8/2029

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