LC-MS-MS Method for Determination of Metolazone in Human Plasma

A rapid, sensitive and specific method for quantification of metolazone in human plasma using metaxalone as internal standard is described. Sample preparation involved a simple liquid-liquid extraction procedure. The extract was analyzed by high performance liquid chromatography coupled to electrosp...

Full description

Bibliographic Details
Main Authors: Shikha M. N. Roy, Kiran V. Mangaonkar, Santosh. M. Yetal, Santosh. S. Joshi
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2008/425974