L-dopa response pattern in a rat model of mild striatonigral degeneration.

L-dopa response pattern in a rat model of mild striatonigral degeneration.

<h4>Background</h4>Unresponsiveness to dopaminergic therapies is a key feature in the diagnosis of multiple system atrophy (MSA) and a major unmet need in the treatment of MSA patients caused by combined striatonigral degeneration (SND). Transgenic, alpha-synuclein animal models do not r...

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Bibliographic Details
Main Authors: Christine Kaindlstorfer, Nadia Stefanova, Joanna Garcia, Florian Krismer, Máté Döbrössy, Georg Göbel, Kurt Jellinger, Roberta Granata, Gregor Karl Wenning
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218130

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https://doi.org/10.1371/journal.pone.0218130

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