ETS1, ELK1, and ETV4 Transcription Factors Regulate Angiopoietin-1 Signaling and the Angiogenic Response in Endothelial Cells

ETS1, ELK1, and ETV4 Transcription Factors Regulate Angiopoietin-1 Signaling and the Angiogenic Response in Endothelial Cells

BackgroundAngiopoietin-1 (Ang-1) is the main ligand of Tie-2 receptors. It promotes endothelial cell (EC) survival, migration, and differentiation. Little is known about the transcription factors (TFs) in ECs that are downstream from Tie-2 receptors.ObjectiveThe main objective of this study is to id...

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Bibliographic Details
Main Authors: Sharon Harel, Veronica Sanchez, Alaa Moamer, Javier E. Sanchez-Galan, Mohammad N. Abid Hussein, Dominique Mayaki, Mathieu Blanchette, Sabah N. A. Hussain
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Physiology
Subjects:
angiogenesis
angiopoietins
endothelial cells
cell signaling
transcription factors
cell migration
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.683651/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.683651/full

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