Development of an aptamer-based concentration method for the detection of Trypanosoma cruzi in blood.

Trypanosoma cruzi, a blood-borne parasite, is the etiological agent of Chagas disease. T. cruzi trypomastigotes, the infectious life cycle stage, can be detected in blood of infected individuals using PCR-based methods. However, soon after a natural infection, or during the chronic phase of Chagas d...

Full description

Bibliographic Details
Main Authors: Rana Nagarkatti, Vaibhav Bist, Sirena Sun, Fernanda Fortes de Araujo, Hira L Nakhasi, Alain Debrabant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3425475?pdf=render