Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19—The Role of RAGE-RAS Crosstalk

The receptor for advanced glycation-end products (RAGE) is a multiligand receptor with a role in inflammatory and pulmonary pathologies. Hyperactivation of RAGE by its ligands has been reported to sustain inflammation and oxidative stress in common comorbidities of severe COVID-19. RAGE is essential...

Full description

Bibliographic Details
Main Authors: Sara Chiappalupi, Laura Salvadori, Rosario Donato, Francesca Riuzzi, Guglielmo Sorci
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/6/876