Cell type specific alterations in interchromosomal networks across the cell cycle.

The interchromosomal organization of a subset of human chromosomes (#1, 4, 11, 12, 16, 17, and 18) was examined in G1 and S phase of human WI38 lung fibroblast and MCF10A breast epithelial cells. Radial positioning of the chromosome territories (CTs) was independent of gene density, but size depende...

Full description

Bibliographic Details
Main Authors: Andrew J Fritz, Branislav Stojkovic, Hu Ding, Jinhui Xu, Sambit Bhattacharya, Ronald Berezney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4183423?pdf=render