Composite endpoints in COPD: clinically important deterioration in the UPLIFT trial

Abstract Background Assessments of lung function, exacerbations and health status are common measures of chronic obstructive pulmonary disease (COPD) progression and treatment response in clinical trials. We hypothesised that a composite endpoint could more holistically assess clinically important d...

Full description

Bibliographic Details
Main Authors: Klaus F. Rabe, David M. G. Halpin, MeiLan K. Han, Marc Miravitlles, Dave Singh, Lars Grönke, Florian Voß, Fernando J. Martinez
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-020-01431-y