Multi-targeted Antisense Oligonucleotide Delivery by a Framework Nucleic Acid for Inhibiting Biofilm Formation and Virulence

Multi-targeted Antisense Oligonucleotide Delivery by a Framework Nucleic Acid for Inhibiting Biofilm Formation and Virulence

Abstract Biofilm formation is responsible for numerous chronic infections and represents a serious health challenge. Bacteria and the extracellular polysaccharides (EPS) cause biofilms to become adherent, toxic, resistant to antibiotics, and ultimately difficult to remove. Inhibition of EPS synthesi...

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Bibliographic Details
Main Authors: Yuxin Zhang, Xueping Xie, Wenjuan Ma, Yuxi Zhan, Chenchen Mao, Xiaoru Shao, Yunfeng Lin
Format: Article
Language:English
Published: SpringerOpen 2020-03-01
Series:Nano-Micro Letters
Subjects:
Biofilm
Framework nucleic acid
Multi-targeting
Antisense oligonucleotide
Delivery system
Online Access:http://link.springer.com/article/10.1007/s40820-020-0409-3

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http://link.springer.com/article/10.1007/s40820-020-0409-3

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