Whole blood RNA sequencing reveals a differential transcriptomic profile associated with cervical insufficiency: a pilot study

Whole blood RNA sequencing reveals a differential transcriptomic profile associated with cervical insufficiency: a pilot study

Abstract Background The uterine cervix is a mechanical and immunological barrier against ascending infection during pregnancy. Cervical insufficiency (CI), a painless cervical dilation that occurs in the mid-trimester, is an important cause of extremely preterm birth. We hypothesized that women with...

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Bibliographic Details
Main Authors: Ga-Hyun Son, So Yeon Choi, Yeon-Ji Ju, Keun-Young Lee, Jae Jun Lee, Ji-Eun Song, Youngmi Kim, Sung Taek Park
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Reproductive Biology and Endocrinology
Subjects:
Alpha defensin
Cervical insufficiency
Pregnancy
Preterm birth
RNA-Seq
Online Access:https://doi.org/10.1186/s12958-021-00715-2

Internet

https://doi.org/10.1186/s12958-021-00715-2

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