Structural basis of RND-type multidrug exporters

Structural basis of RND-type multidrug exporters

Bacterial multidrug exporters are intrinsic membrane transporters that act as cellular self-defense mechanism. The most notable characteristics of multidrug exporters is that they export a wide range of drugs and toxic compounds. The overexpression of these exporters causes multidrug resistance. Mul...

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Bibliographic Details
Main Authors: Akihito eYamaguchi, Ryosuke eNakashima, Keisuke eSakurai
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Microbiology
Subjects:
crystal structure
multidrug resistance
RND
ACRB
multidrug exporter
functional-rotation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00327/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00327/full

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