Heme oxygenase-1-modified bone marrow mesenchymal stem cells combined with normothermic machine perfusion to protect donation after circulatory death liver grafts

Heme oxygenase-1-modified bone marrow mesenchymal stem cells combined with normothermic machine perfusion to protect donation after circulatory death liver grafts

Abstract Background Donation after circulatory death (DCD) liver grafts have a poor prognosis after transplantation. We investigated whether the outcome of DCD donor organs can be improved by heme oxygenase 1 (HO-1)-modified bone marrow-derived mesenchymal stem cells (BMMSCs) combined with normother...

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Bibliographic Details
Main Authors: Huan Cao, Liu Yang, Bin Hou, Dong Sun, Ling Lin, Hong-Li Song, Zhong-Yang Shen
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Stem Cell Research & Therapy
Subjects:
Bone marrow mesenchymal stem cells
Donation after circulatory death
Normothermic machine perfusion
Orthotopic liver transplantation
Online Access:http://link.springer.com/article/10.1186/s13287-020-01736-1

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http://link.springer.com/article/10.1186/s13287-020-01736-1

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