Effect of <i>CYP3A5</i> on the Once-Daily Tacrolimus Conversion in Stable Liver Transplant Patients

Effect of <i>CYP3A5</i> on the Once-Daily Tacrolimus Conversion in Stable Liver Transplant Patients

Cytochrome P450 (<i>CYP</i>) <i>3A5</i> polymorphism influences tacrolimus metabolism, but its effect on the drug pharmacokinetics in liver transplant recipients switched to once-daily extended-release formulation remains unknown. The aim of this study is to analyze the effec...

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Bibliographic Details
Main Authors: Jong Man Kim, Je Ho Ryu, Kwang-Woong Lee, Suk Kyun Hong, Kwangho Yang, Gyu-Seong Choi, Young-Ae Kim, Ju-Yeun Lee, Nam-Joon Yi, Choon Hyuck David Kwon, Chong Woo Chu, Kyung-Suk Suh, Jae-Won Joh
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Journal of Clinical Medicine
Subjects:
pharmacokinetics
immunosuppression
tacrolimus
Online Access:https://www.mdpi.com/2077-0383/9/9/2897

Internet

https://www.mdpi.com/2077-0383/9/9/2897

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