Modeling and Simulation of VEGF Receptors Recruitment in Angiogenesis

Angiogenesis, the process of new blood vessel formation from preexisting ones, plays a pivotal role in tumor growth. Vascular endothelial growth factor receptor-2 (VEGFR2) is the main proangiogenic tyrosine kinase receptor expressed by endothelial cells (ECs). VEGFR2 binds different ligands triggeri...

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Bibliographic Details
Main Authors: A. Salvadori, V. Damioli, C. Ravelli, S. Mitola
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Mathematical Problems in Engineering
Online Access:http://dx.doi.org/10.1155/2018/4705472