Asynchronous expression of myeloid antigens in leukemic cells in a PML/RARalpha transgenic mouse model

Asynchronous expression of myeloid antigens in leukemic cells in a PML/RARalpha transgenic mouse model

Acute promyelocytic leukemia (APL) is characterized by the expansion of blasts that resemble morphologically promyelocytes and harbor a chromosomal translocation involving the retinoic acid receptor a (RARa) and the promyelocytic leukemia (PML) genes on chromosomes 17 and 15, respectively. The expre...

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Bibliographic Details
Main Authors: B.A.A. Santana, M.C. Pintão, R.S. Abreu e Lima, P.S. Scheucher, G.A.S. Santos, A.B. Garcia, R.P. Falcão, E.M. Rego
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2006-05-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Acute promyelocytic leukemia
Acute myelogenous leukemia
Transgenic mice
Flow cytometry
Leukemogenesis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000500008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2006000500008

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