Could CD4 Capture by CD8+ T Cells Play a Role in HIV Spreading?

CD8+ T cells have been shown to capture plasma membrane fragments from target cells expressing their cognate antigen, a process termed “trogocytosis”. Here, we report that human CD4, the Human Immunodeficiency Virus (HIV) receptor, can be found among the proteins transferred by trogocytosis. CD4 is...

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Bibliographic Details
Main Authors: Anne Aucher, Isabel Puigdomènech, Etienne Joly, Bonaventura Clotet, Denis Hudrisier, Julià Blanco
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/907371