Effects of Whole-Body Adenylyl Cyclase 5 (<i>Adcy5</i>) Deficiency on Systemic Insulin Sensitivity and Adipose Tissue

Effects of Whole-Body Adenylyl Cyclase 5 (<i>Adcy5</i>) Deficiency on Systemic Insulin Sensitivity and Adipose Tissue

Genome-wide association studies have identified adenylyl cyclase type 5 (<i>ADCY5</i>) as candidate gene for diabetes-related quantitative traits and an increased risk of type 2 diabetes. Mice with a whole-body deletion of <i>Adcy5 (Adcy5</i><sup>–/<i>–</i>&...

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Bibliographic Details
Main Authors: Sebastian Dommel, Anne Hoffmann, Claudia Berger, Matthias Kern, Nora Klöting, Aimo Kannt, Matthias Blüher
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
adipocyte size
insulin resistance
metabolism
gene expression
<i>Adcy5</i> knockout
running activity
Online Access:https://www.mdpi.com/1422-0067/22/9/4353

Internet

https://www.mdpi.com/1422-0067/22/9/4353

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