Necrosis: Linking the Inflammasome to Inflammation
In this issue of Cell Reports, Cullen et al. demonstrate that the release of mature interleukin-1β relies on necrotic plasma membrane permeabilization. Thus, caspases may have evolved to modulate the inflammatory potential of cell death, not to execute it.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2015-06-01
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| Series: | Cell Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S221112471500577X |