A confinable home-and-rescue gene drive for population modification
Homing-based gene drives, engineered using CRISPR/Cas9, have been proposed to spread desirable genes throughout populations. However, invasion of such drives can be hindered by the accumulation of resistant alleles. To limit this obstacle, we engineer a confinable population modification home-and-re...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2021-03-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/65939 |