Immunoneutralization of TGFβ1 Improves Skeletal Muscle Regeneration: Effects on Myoblast Differentiation and Glycosaminoglycan Content

When injured by crushing, the repair of the slow-twitch soleus rat muscle, unlike the fast-twitch EDL, is associated with fibrosis. As TGFβ1, whose activity can be controlled by glycosaminoglycans (GAG), plays a major role in fibrosis, we hypothesized that levels of TGFβ1 and GAG contents could acco...

Full description

Bibliographic Details
Main Authors: M. Zimowska, A. Duchesnay, P. Dragun, A. Oberbek, J. Moraczewski, I. Martelly
Format: Article
Language:English
Published: Hindawi Limited 2009-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2009/659372