Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation

Combining Cell-Free Protein Synthesis and NMR Into a Tool to Study Capsid Assembly Modulation

Modulation of capsid assembly by small molecules has become a central concept in the fight against viral infection. Proper capsid assembly is crucial to form the high molecular weight structures that protect the viral genome and that, often in concert with the envelope, allow for cell entry and fusi...

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Bibliographic Details
Main Authors: Shishan Wang, Marie-Laure Fogeron, Maarten Schledorn, Marie Dujardin, Susanne Penzel, Dara Burdette, Jan Martin Berke, Michael Nassal, Lauriane Lecoq, Beat H. Meier, Anja Böckmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Molecular Biosciences
Subjects:
cell-free protein synthesis
NMR
proton detection
capsid
HBV—hepatitis B virus
assembly modulation
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00067/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2019.00067/full

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