Nobiletin, a polymethoxy flavonoid, exerts anti-allergic effect by suppressing activation of phosphoinositide 3-kinase

Nobiletin, a polymethoxy flavonoid, exerts anti-allergic effect by suppressing activation of phosphoinositide 3-kinase

Nobiletin is a polymethoxy flavonoid present in fruit tissues of citrus species and has been reported to suppress degranulation of RBL-2H3 cells. However, the detailed mechanism is still unknown. In this study the mechanism of suppressive effect of nobiletin on degranulation of RBL-2H3 cells was exa...

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Bibliographic Details
Main Authors: Sayo Onishi, Kosuke Nishi, Sho Yasunaga, Ayako Muranaka, Kazutaka Maeyama, Ayumu Kadota, Takuya Sugahara
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Functional Foods
Subjects:
Nobiletin
Anti-allergic activity
RBL-2H3 cells
Phosphatidylinositol 3-kinase
Degranulation
Wortmannin
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464613002995

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http://www.sciencedirect.com/science/article/pii/S1756464613002995

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